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First identified in human plasma, its concentration declines significantly with agefrom approximately 200 ng/mL in youth to 80 ng/mL by the age of 60 (Pickart and Margolina 2018)

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Chakraborty R, Renu K, Eladl MA, El-Sherbiny M, Elsherbini DMA, Mirza AK, Vellingiri B, Iyer M, Dey A, Valsala Gopalakrishnan A (2022) Mechanism of chromium-induced toxicity in lungs, liver, and kidney and their ameliorative agents

When exposed to ultraviolet light, it readily breaks down into compounds like dehydroascorbic acid and 2,3-diketogulonic acid, which diminishes its biological efficacy (Ahmad et al., 2011

The results showed that the concentration of H 2 O 2 in the cell supernatant treated with NP4 was higher compared to the supernatant of cells treated with Ru(II)-OH and NP2 (Fig