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In delta and epsilon GSTs, His-38 is maintained in most cases as a polar or charged residue and His-50 is conserved as part of an NPQHTVPTL motif
According to the NIH criteria, a PCOS diagnosis necessitates the presence of both chronic anovulation and clinical or biochemical evidence of hyperandrogenism, after excluding other underlying causes
It neutralizes free radicals before they can damage cellular DNA and proteins
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The potential therapeutic effects of targeting this pathway are attracting increasing attention
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