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In the research that exists, GHK-Cu has a reassuring safety profile: it occurs naturally in the body, is active at tiny (nanomolar) amounts, and has been used in topical cosmetics for decades without notable problems.[2] That track record, though, is mostly about topical use the safety of injected GHK-Cu has not been established in controlled human trials, and it's not an approved drug

The effects of angiotensin IV analogs on long-term potentiation within the CA1 region of the hippocampus in vitro. Brain Res 897(1-2): 114-21

Distinct Anxiolytic Profile Anxiolytic effects distinct from benzodiazepines emerged in shock probe/burying and light/dark tests

COMT and MTHFR polymorphisms interaction on cognition in schizophrenia: an exploratory study

60 years of POMC: from POMC and MSH to PAM, molecular oxygen, copper and vitamin C