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It functions as a master antioxidant and phase II detoxification cofactor, supporting both oxidative stress reduction and xenobiotic metabolism

Rafehi, H., El-Osta, A

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A Phase 1B trial in GBA1associated Parkinsons disease of BIA286156, a glucocerebrosidase activator

Furthermore, the disrupted basement membrane serves as a direct migratory pathway for inflammatory cell infiltration, thereby exacerbating the inflammatory response within the brain parenchyma (156)