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Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms

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Mendelian randomisation finds no causal association between urate and Parkinsons disease progression

The writer enzyme is hypothesized to catalyze the transfer of lactate-derived metabolites (likely via lactoyl-CoA) to lysine residues on proteins, resulting in lactylation modifications that influence gene expression, chromatin structure, and cellular phenotype

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And sterile technique prevents contamination that accelerates biological degradation on top of the chemical pathways