These beneficial effects may be due to the formation of detour circuitswhich encompass spared tissue surrounding the lesionand could reconnect locomotor circuits [69], thus enabling afferent inputs to be processed and conveyed to the cortex [73] and improving spinal reflexes, even below the injury [74]
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Published in Pharmaceuticals by Sikiric and colleagues, the comprehensive review synthesizes decades of preclinical research demonstrating BPC-157s remarkable ability to modulate dopaminergic, serotonergic, glutamatergic, GABAergic, and nitric oxide systems simultaneously
