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[DOI] [PubMed] [Google Scholar] 385

A novel small-molecule antagonist enhances the sensitivity of osteosarcoma to cabozantinib in vitro and in vivo by targeting DNMT-1 correlated with disease severity in human patients

YeSSuLShanPYeBWuSLiangGet al

Circulation Research, 88 (9), 888894

Results The number of human genes associated with stem cell function was 57 genes in the range of increases of 50% UP and 46 genes in the range of decreases of 50% DOWN

While the samples treated with Zn (0.5 g L 1 ) x GSH (0.4 g L 1 ), Zn (0 g L 1 ) x GSH (0.4 g L 1 ) and Zn (1 g L 1 ) x GSH (0.2 g L 1 ) give GTS percentage 69.44%, 72.22% and 75%, respectively