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Phase 2 trials (Jastreboff et al., NEJM, 2023) have shown it to be highly effective for weight reduction in adults with obesity

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IM administration should be done with an appropriate needle to reach muscle tissue, and the site should be rotated (for example, alternate buttocks) if injections are repeated regularly to avoid soreness

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For most people with a vitamin B12 deficiency, oral supplements are an effective way to bring your levels up to normal, says Foxx, and research backs this up (2)