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DAVID database performed Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis

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10.1073/pnas.96.24.14165 86 MittlerR.VanderauweraS.GolleryM.Van BreusegemF

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In mammalian nervous systems, many different types of chemical substances, including amino acids (e.g., glutamate), monoamines (e.g., dopamine, norepinephrine), acetylcholine, peptides (e.g., substance P), serve as neurotransmitters to bind their corresponding receptors, then activate ion channels, and consequently produce ion flux 1 , thereby inducing membrane potential changes that lead to signal propagation for neurotransmission 1,2,3,4