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Work in GHRH-knockout murine models demonstrated that daily CJC-1295 restored somatotroph cell mass, as evidenced by increased GH mRNA and total pituitary RNA: CJC-1295 caused an increase in total pituitary RNA and GH mRNA, suggesting that proliferation of somatotroph cells had occurred Physiology Journals

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To view a copy of this licence, visit About this article Cite this article Koyama, Y., Kobayashi, Y., Hirota, I