None of the Marketing Authorisation Holders in the UK use any clinical evidence for optimal dosage of 3 monthly treatment and base the information written in their Patient Information Leaflet upon BNF Guidelines and the Martindale Drug Reference book
The extract worked in synergy with paclitaxel, causing DNA damage, enhancing apoptosis, and inhibiting proliferation of metastatic breast cancer cells (Ghoneum 2014)
When someone experiences persistent levels of stress and thus increased cortisol, they may experience dysregulation of neurotransmitters such as dopamine, serotonin, and norepinephrine
So this is a very interesting intersection
However, the effect of biological sex on the relationship between GSH levels and cognitive function has not been previously explored
Antioxidative enzymes provide first line defense and whether or not these can be sufficiently supplemented remains controversial