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Typical 16-Week Titration Pre-blended CagriSema Titration (mirrors REDEFINE protocol structure) Week 14 Cagrilintide 0.25 mg Semaglutide 0.25 mg Notes Initiation: gastrointestinal tolerability is highest priority
Unlike reductionist approaches centered on single metabolites, recent studies emphasize the need to assess panels of interrelated metabolites, which may better capture the complex biochemical alterations underlying disease progression [535]
For MLTSS programs, states develop care management requirements for person-centered needs assessment, service planning, and service coordination that are consistent with CMS guidance and regulations and that are implemented through their contracts with Medicaid managed care organizations (CMS, 2013, 2014c)
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