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Additionally, as a critical and pre-specified subgroup analysis, we focus on exclusive e-cigarette usersindividuals who currently use e-cigarettes but have never smoked traditional cigarettesto minimize the confounding effects of smoking history and to preliminarily explore the potential independent association

the production and sale of roll-your-own or hand-rolled cigarettes, and other forms of tobacco, such as bidis or kreteks, have not been accounted for in the analyses

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Similarly, if the patient is experiencing withdrawal symptoms or other nicotine-induced disorders, these should be recorded

4 Since the 2013 tobacco tax passed, smoking among Minnesotas 11th graders has been cut in half

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