Ferroptosis, an iron-dependent form of programmed cell death first identified by Dixon et al., is characterized by excessive intracellular iron accumulation, lipid peroxidation and distinct biochemical and morphological features (Liu et al., 2021)
Asian vitiligo patients showed lower levels of GPx than the controls, Caucasian populations, and healthy controls [81]
Pharmacol Res (2015) 99:6373
Influence of thyroid hormones on L--glycerophosphate dehydrogenases and other dehydrogenases in various organs of the rat
However, off-target effects still cause the risk of normal cell damage and serious side effects
Moreover, its skin-brightening and anti-aging properties have made it a popular beauty-enhancing ingredient in many skin care products in recent years