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Metformin like other AEDs such as tiagabine and vigabatrin can trigger absence seizure by increasing the availability of GABA which induces stimulation of GABA-B (Yang et al

Because certainly, histamine, being an arousal neurotransmitter and part of the stress response, means if there are issues with the enzymes that clear stress hormones, were going to see a knock-on effect to histamine

Store in a cool, dry place, away from light and heat source

doi: 10.1016/j.ijbiomac.2025.145602 32 WangWLiHYangDCaiWCheHLiH

Detection windows vary by specific compound

The introduction system to the instrument was a PerkinElmer S23 autosampler coupled to a SeaSpray glass nebulizer fitted to a quartz cyclonic spray chamber