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Additionally, research has shown that Modified Yijing Decoction can improve ovarian reserve function in cyclophosphamide-induced DOR rats by upregulating the expression of TGF- superfamily members, including AMH, INHB, TGF-1, TGF-1R, and BMP-15 [65]

Proper dosing requires slow titration to maximum tolerated doses, typically semaglutide 2.4mg weekly plus cagrilintide 2.4mg weekly, though conservative approaches using lower maintenance doses work well for many

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It is activated in more than 50% of BCs and is associated with decreased overall survival [95, 96]