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This benefits people with low stomach acid (including many people over the age of 50) or those who take acid blockers such as Pepcid or Zantac, or proton pump inhibitors such as Prevacid, or Prilosec, who are at an increased risk for B-12 deficiency

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It is less likely to cause moderate issues but micro-manages dosing

The current status of homocysteine as a risk factor for cardiovascular disease: a mini review