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Head-to-head trials suggest tirzepatide achieves approximately 24% additional weight loss compared to semaglutide, though individual response varies significantly based on genetic and metabolic factors

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Afr J Biotechnol 13(32):33233331

Saich, T

Figure 8 3.5 Chronic fatigue syndrome (CFS) A growing body of clinical evidence shows that the gut microbiota plays a critical role in CFS, with consistently observed reductions in butyrate-producing bacteria and enrichment of Enterobacteriaceae , together with frequent depletion of anti-inflammatory taxa such as Faecalibacterium (Knig et al., 2021