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This allostatic equilibrium does not appear to alter the proBDNF/BDNF ratio, which has been associated with processes that counteract cocaine-induced neurotoxic damage [31]

In the past twenty years, and mainly by repurposing drugs use, molecules have been identified but to date, clinical trials display moderated efficiency

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This mitochondrial DNA polymorphism, thought to alter MOTS-cs function slightly, was more frequent in long-lived individuals, hinting that MOTS-c could influence human lifespan

Reactive oxygen species, ionizing radiation, and certain chemicals can cause single- and double-strand breaks in DNA 3,4

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