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When vitamin B12 is supplemented and the skin appearance deteriorates, the folic acid and biotin status in the blood should also be measured

References Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM

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Once pathological aetiologias have been discarded, it is relevant to question the supply and status of vitamins and minerals and to provide nutritional advice first aiming at promoting balanced food choices, then focusing on the use of vitamin and mineral supplementation

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While not a direct fat-loss solution, they support metabolism and energy, which can aid weight management