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AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation

alternatively, the dose of drug being administered are temporarily reduced or temporarily suspended for a certain length of time (i.e., a drug holiday)

216 The fusion of mitochondria was affected by OPA1, which can change mitochondrial inner membrane fusion

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