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in turn, these mechanisms lead to melanocytes destruction (via IS stimulation) and to the impossibility of their maturation and resynthesis

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both NNMT and resveratrol modulate Sirtuin 1 (Sirt1) activity 83,84 , and resveratrol 83 and 5A-1MQ increase Parasutterella abundance, suggesting a potential causal link

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Mathiesen DS, Bagger JI, Knop FK

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