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Silencing of miR122 has been shown to upregulate CAT-1 ( SLC7A1 ) expression, and subsequently increase arginine uptake to maintain large intracellular arginine pools for nitric oxide (NO) synthesis, resulting in increased resistance to the multi-kinase inhibitor sorafenib (Kishikawa et al., 2015)

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Subsequently, the supernatant was evaporated under a nitrogen stream at 40 C

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137 In addition, adipose MSCs, hair follicle MSCs, and dental pulp MSCs reduce inflammatory responses, promote mucosal healing, and improve intestinal barrier function