Important safety questions include product purity, dose accuracy, drug interactions, liver and kidney considerations, blood sugar changes, cardiovascular risk, pregnancy or breastfeeding status, and long-term exposure
doi:10.1046/j.1365-2958.2001.02479.x
However, in vivo studies primarily in humans are needed to confirm these promising preclinical findings
Alves R, Ferreira CGM, Silva MVda, Vieira Filho LD, Silva Junior VAda, Melo IMFde, et al
The dysregulation across the different neurotransmitter systems may contribute to the formation of habitual and inflexible unhealthy food choices, which have been implicated in the development of BED (124)
(2007) demonstrated that exposing human astrocytes to the HIV-1 envelope glycoprotein gp120 led to significant neurotoxic consequences, including diminished cell viability, increased apoptosis, lipid peroxidation, and, reduced expression of GS [125]